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Toshifumi Hibi Selected Research

Inflammation (Inflammations)

8/2021Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease.
4/2018Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study.
1/2018Correction to: Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study.
1/2018Th17 plasticity and its relevance to inflammatory bowel disease.
10/2017Steroid-refractory extensive enteritis complicated by ulcerative colitis successfully treated with adalimumab.
1/2017Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.
1/2017Usefulness of fecal calprotectin for the early prediction of short-term outcomes of remission-induction treatments in ulcerative colitis in comparison with two-item patient-reported outcome.
10/2016Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages.
3/2016Investigation of a High-Dose pH-Dependent-Release Mesalazine on the Induction of Remission in Active Crohn's Disease.
9/2014Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis.
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Toshifumi Hibi Research Topics

Disease

113Ulcerative Colitis
10/2022 - 01/2002
70Crohn Disease (Crohn's Disease)
06/2022 - 08/2002
41Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2022 - 09/2002
40Neoplasms (Cancer)
01/2022 - 07/2003
38Inflammation (Inflammations)
08/2021 - 12/2002
36Colitis
10/2020 - 02/2003
33Infections
03/2021 - 09/2004
20Hemorrhage
05/2022 - 12/2005
15Stomach Neoplasms (Stomach Cancer)
01/2014 - 02/2003
12Chronic Hepatitis C
01/2015 - 05/2005
10Ulcer
01/2020 - 07/2005
9Necrosis
05/2022 - 12/2008
9Non-alcoholic Fatty Liver Disease
01/2018 - 12/2005
9Dyspepsia (Indigestion)
02/2016 - 11/2005
9Liver Cirrhosis (Hepatic Cirrhosis)
07/2014 - 06/2007
8Carcinogenesis
12/2013 - 07/2003
8Fibrosis (Cirrhosis)
11/2013 - 09/2005
7Hepatocellular Carcinoma (Hepatoma)
09/2013 - 01/2005
6Colorectal Neoplasms (Colorectal Cancer)
04/2018 - 07/2003
6Hepatitis
01/2014 - 01/2008
6Pancreatic Neoplasms (Pancreatic Cancer)
02/2013 - 06/2009
6Fatty Liver
01/2013 - 11/2004
6Liver Diseases (Liver Disease)
12/2012 - 06/2007
6Gastritis
05/2010 - 09/2004
5Tuberculosis (Tuberculoses)
08/2021 - 01/2018
5Body Weight (Weight, Body)
01/2021 - 07/2005
5Polyps
04/2016 - 10/2010
5Neoplasm Metastasis (Metastasis)
12/2014 - 11/2004
5Ischemia
02/2012 - 01/2005
5Atrophy
12/2011 - 09/2004
4Pathologic Constriction (Stenosis)
06/2020 - 10/2007
4Disease Progression
04/2018 - 06/2008
4Stomach Ulcer (Gastric Ulcer)
02/2013 - 12/2004
4Lymphatic Metastasis
01/2013 - 02/2003
4Carcinoma (Carcinomatosis)
01/2013 - 11/2003

Drug/Important Bio-Agent (IBA)

29Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2021 - 06/2003
26Infliximab (Remicade)FDA Link
05/2022 - 12/2005
20Mesalamine (Mesalazine)FDA LinkGeneric
01/2022 - 08/2009
19Adalimumab (Humira)FDA Link
01/2022 - 03/2012
17SteroidsIBA
01/2022 - 01/2003
17CytokinesIBA
12/2013 - 12/2002
16Pharmaceutical PreparationsIBA
01/2022 - 11/2004
11Monoclonal AntibodiesIBA
08/2021 - 02/2003
11InterferonsIBA
01/2015 - 05/2005
10Biological ProductsIBA
01/2022 - 09/2002
10Proteins (Proteins, Gene)FDA Link
11/2015 - 11/2003
10GhrelinIBA
12/2012 - 09/2004
9Capsules (Microcapsules)IBA
04/2021 - 10/2007
9Therapeutic UsesIBA
04/2018 - 02/2003
8vedolizumabIBA
01/2022 - 01/2019
8DNA (Deoxyribonucleic Acid)IBA
11/2021 - 05/2005
8MicroRNAs (MicroRNA)IBA
12/2013 - 01/2009
8Proton Pump InhibitorsIBA
12/2013 - 01/2005
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021 - 12/2015
7Biomarkers (Surrogate Marker)IBA
12/2019 - 08/2009
7AntigensIBA
01/2018 - 03/2004
7Ribavirin (Virazole)FDA LinkGeneric
01/2015 - 10/2006
7Messenger RNA (mRNA)IBA
07/2013 - 09/2007
7EnzymesIBA
01/2013 - 09/2005
7Interleukin-12 (IL 12)IBA
06/2012 - 12/2002
62-mercaptopurineIBA
01/2022 - 01/2015
6Interleukin-23 (Interleukin 23)IBA
01/2022 - 11/2005
6C-Reactive ProteinIBA
01/2022 - 02/2003
6Budesonide (Pulmicort)FDA LinkGeneric
01/2020 - 04/2013
6Dextran SulfateIBA
01/2014 - 08/2003
6Anti-Bacterial Agents (Antibiotics)IBA
12/2012 - 11/2004
6InterleukinsIBA
09/2011 - 06/2003
5Interleukin-10 (Interleukin 10)IBA
10/2016 - 03/2010
5Interleukin-6 (Interleukin 6)IBA
09/2015 - 04/2004
5Immunoglobulin G (IgG)IBA
12/2013 - 01/2007
5Cisplatin (Platino)FDA LinkGeneric
01/2013 - 11/2003
5Toll-Like Receptors (Toll-Like Receptor)IBA
12/2012 - 01/2006
5AcidsIBA
12/2011 - 01/2005
5Ethanol (Ethyl Alcohol)IBA
12/2009 - 12/2004
4tofacitinibIBA
10/2022 - 01/2018
4Leukocyte L1 Antigen Complex (Calgranulin)IBA
01/2022 - 01/2017
4Immunologic Factors (Immunomodulators)IBA
01/2022 - 02/2020
4Immunosuppressive Agents (Immunosuppressants)IBA
01/2021 - 01/2002
4TabletsIBA
07/2020 - 01/2017
4Azathioprine (Imuran)FDA LinkGeneric
09/2019 - 01/2003
4CholesterolIBA
10/2017 - 01/2012
4Prednisolone (Predate)FDA LinkGeneric
03/2015 - 06/2005
4Carbon Tetrachloride (Tetrachloromethane)IBA
07/2014 - 01/2012
4Transforming Growth Factors (Transforming Growth Factor)IBA
01/2014 - 03/2011
4NF-kappa B (NF-kB)IBA
02/2011 - 01/2003
4Interleukin-7 (Interleukin 7)IBA
09/2010 - 04/2005
4Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2009 - 09/2005
4AldehydesIBA
03/2007 - 07/2005
4AcetaldehydeIBA
03/2007 - 07/2005
4Interferon-betaIBA
09/2006 - 05/2005
3Janus Kinase InhibitorsIBA
10/2022 - 04/2018

Therapy/Procedure

94Therapeutics
03/2022 - 01/2002
13Drug Therapy (Chemotherapy)
01/2013 - 02/2003
11Blood Component Removal (Apheresis)
04/2020 - 05/2004
8Remission Induction
01/2022 - 09/2010
4Restorative Proctocolectomy
10/2020 - 10/2007
4Colectomy
07/2020 - 11/2010
4Liver Transplantation
03/2015 - 01/2009
4Ligation
07/2014 - 10/2010
3Blood Transfusion (Blood Transfusions)
05/2022 - 09/2007